Domi is day to day with an undisclosed injury that occured in a game against the Devils last week. He played through the pain on Saturday.
With these two players absent, Sheldon Keefe once again decided to make changes in his top lines. Marner got back with Matthews on the first line, while Knies, Tavares and Nylander formed the second line.
"Max Domi is not practising today after a day off on Sunday.
Domi was injured last Thursday against the Devils but played on Saturday.
The Leafs and the Panthers could meet in the playoffs once again this year, and tomorrow night's game will set the tone for what's coming. There's also a chance that fans could get to see Auston Matthews reach (or exceed) the 70-goal mark.